Sometimes oral thrush may spread to the roof of your mouth, your gums or tonsils, or the back of your throat.Although oral thrush can affect anyo… American Heart Association: "Possible Side Effects of Drugs That Lower Blood Pressure. ", National Institutes of Health: "Taste Disorders.". Cancer Treatment. You are more likely to develop mucositis after taking chemotherapy drugs if you drink alcohol, use tobacco, do not take care of your teeth and gums, are dehydrated, or have diabetes, HIV, or kidney disease. Be sure to try new foods when you're feeling good so you don't develop more food dislikes. These may help stimulate your taste buds, increase the flow of saliva and get rid of any unpleasant tastes in your mouth. ", Cancer Research UK: "Types and Causes of Mouth Problems. Doctors think that certain chemotherapy drugs, including methotrexate and 5-fluorouracil, trigger a complex pattern of biological changes that damage the cells that make up the mucous membranes. Taste and smell changes can often affect your appetite. Your sense of taste should return to normal after treatment ends, but it may take some time. Heidelbaugh, J. Lemons are great for the senses and your taste buds could perk up with a slice of the zesty fruit. Mucositis is inflammation of the moist tissue lining the mouth and digestive tract. Testing should be considered if the patient is not meeting goals of rehabilitation, because altered taste perception may lead to depression, weight loss, and malnutrition, all of which may act to confound rehabilitation efforts.. Food tasting too salty or sweet. Primary Care Companion Journal of Clinical Psychiatry, 2006. I could not find research about directly re-stimulating the taste buds, but at the very least, supporting the person … This happens whether I use brand name mino or generic and whether I take a 50 mg capsule or a 100 mg capsule. Always consult your doctor before taking any drug and follow your doctor's directions. Chemotherapy medicines that can cause mucositis include: A mouth ulcer refers to an open (ulcerated) sore that occurs inside the mouth or on the tongue. "Â, Cancer Research UK: "Types and Causes of Mouth Problems. Today, tetracycline and related antibiotics are not recommended during pregnancy or in young children (under age 8) whose teeth are still forming. Drink tart juices to “mask” the taste of medicine mouth: cranberry, lemonade, pineapple juice, orange juice, etc. Schiffman et al17 studied the taste effects of topical application of 62 drugs to the lingual surface in human subjects. To clear your taste buds, rinse your mouth out with ginger ale, tea, salted water, or a spoonful of baking soda dissolved in a glass water. I've never had this happen with any other medication or nutritional supplement but minocycline. Upper respiratory infections, whether viral or bacterial, can cause … This hole is actually a break in the moist tissue (mucous membrane) that lines the mouth. The sense of taste is an oral chemical sense in mammals that is involved in the choice of foods. Zithromax - Can Z-Pak affect taste buds(all foods taste sweet or salty) and cause thrush on tongue? Among them are cardiovascular agents, central nervous system stimulants, nonsteroidal anti-inflammatory drugs, respiratory inhalants and smoking cessation products such as nicotine skin patches. – Schwarz (carbidopa-levodopa orally disintegrating tablets), PATANOL® – Alcon (olopatadine hydrochloride ophthalmic solution 0.1%), PAXIL CR? Extended-ReleaseTablets – Andrx Labs (Lovastatin), AMERGE® – GlaxoSmithKline (naratriptan hydrochloride) Tablets, ANZEMET® Injection – Aventis (dolasetron mesylate injection), ANZEMET® – Aventis (dolasetron mesylate) Tablets, AQUAMEPHYTON® – Merck (Phytonadione) Aqueous Colloidal Solution of Vitamin K1 Injection, ASACOL® – Procter & Gamble Pharmaceuticals (mesalamine) Delayed-Release Tablets, ATROVENT® – Boehringer Ingelheim (ipratropium bromide) Nasal Spray, AVINZA® – Ligand (morphine sulfate extended-release Capsules), AXERT® – Ortho-McNeil (almotriptan malate) Tablets, AZACTAM® – Elan (aztreonam for injection), BACTROBAN NASAL® – GlaxoSmithKline brand of mupirocin calcium ointment, BEXTRA® – Pharmacia & Upjohn valdecoxib tablets, BIAXIN® GRANULES (clarithromycin for oral suspension), BICILLIN® L-A – King (penicillin G benzathine suspension) INJECTION FOR DEEP IM INJECTION, BREVIBLOC – Baxter health care, Concentrate, Injection, Premixed Injection, Double Strength Injection, Double Strength Premixed Injection, BRIMONIDINE TARTRATE – Bausch & Lomb Ophthalmic Solution 0.2% STERILE OPHTHALMIC SOLUTION, CADUET® – Pfizer (amlodipine besylate/atorvastatin calcium), CAMPRAL® – Forest (acamprosate calcium) Delayed-Release Tablets, CARTEOLOL HYDROCHLORIDE – Bausch & Lomb Ophthalmic Solution USP, 1% STERILE OPHTHALMIC SOLUTION, CEDAX® – Shionogi (ceftibuten Capsules) and (ceftibuten for oral suspension) FOR ORAL USE ONLY, CELEXA® – Forest (citalopram hydrobromide) Tablets/Oral Solution, CIPRO® XR – Bayer (ciprofloxacin* extended-release tablets), CIPRODEX® – Alcon (ciprofloxacin 0.3% and dexamethasone 0.1%) Sterile Otic Suspension, COLAZAL® – Salix (balsalazide disodium) Capsules, COMBIVENT® – Boehringer Ingelheim (ipratropium bromide and albuterol sulfate) Inhalation Aerosol Bronchodilator Aerosol, COPAXONE® – Teva Neuroscience (glatiramer acetate injection), COUMADIN – Bristol-Myers Squibb Tablets and Injection, COZAAR® – Merck (losartan potassium tablets), CRIXIVAN® – Merck (INDINAVIR SULFATE) Capsules, CUBICIN® – Cubist (daptomycin for injection), CYTOVENE®-IV – Roche Laboratories (ganciclovir sodium for injection), CYTOVENE® – Roche Laboratories (ganciclovir Capsules), CYTOVENE®-IV – Roche Laboratories (ganciclovir sodium for injection) FOR INTRAVENOUS INFUSION, CYTOVENE® (ganciclovir Capsules) FOR ORAL ADMINISTRATION, DANTRIUM® – Procter & Gamble Pharmaceuticals (dantrolene sodium) Capsules, DENAVIR® – Novartis Consumer, a brand of penciclovir cream, 1%, DEPAKOTE® ER – Abbott (divalproex sodium) Extended-ReleaseTablets, DIFLUCAN® – Pfizer (Fluconazole Tablets) (Injection, Oral Suspension and Tablets), DILAUDID® – Abbott (hydromorphone hydrochloride) Dose Vials, Oral Liquid, Powder, Suppositories, Tablets and injection, DILAUDID® – Abbott (hydromorphone hydrochloride), DIPRIVAN® – AstraZeneca (propofol) Injectable Emulsion FOR IV ADMINISTRATION, DOXIL® – Tibotec (doxorubicin HCl liposome injection) FOR INTRAVENOUS INFUSION ONLY, DUONEB® – Dey (Ipratropium Bromide 0.5 mg/Albuterol Sulfate 3.0 mg*) Inhalation Solution, EFFEXOR® – Wyeth-Ayerst (venlafaxine hydrochloride) Tablets, XR Capsules, ELDEPRYL® – Somerset (SELEGILINE HYDROCHLORIDE) Capsules, ELIGARD® 7.5 mg – Sanofi-Synthelabo (leuprolide acetate for injectable suspension), ESKALITH® – GlaxoSmithKline (lithium carbonate) Capsules, ESKALITH CR® (lithium carbonate) Controlled-Release Tablets, EVOXAC® – Daiichi (cevimeline hydrochloride) Capsules, EXELON® – Novartis (rivastigmine tartrate) Capsules, EXELON® – Novartis (rivastigmine tartrate) Oral Solution, FACTIVE® – Ocient (gemifloxacin mesylate) Tablets, FLONASE® – GlaxoSmithKline (fluticasone propionate) Nasal Spray, FLOXIN® – Ortho-McNeil (ofloxacin) tablets, FLUMADINE® – Forest (rimantadine hydrochloride tablets) Tablets and SYRUP, FML® – Allergan (fluorometholone ophthalmic suspension), FML FORTE® – Allergan (fluorometholone ophthalmic suspension), FOSAMAX® – Merck (alendronate sodium) Tablets and Oral Solution, GABITRIL® – Cephalon (tiagabine hydrochloride) Tablets, GASTROCROM® – Celltech (cromolyn sodium) Oral Concentrate, HIVID® – Roche Laboratories (zalcitabine) Tablets, HYZAAR® 50-12.5 – Merck (losartan potassium-hydrochlorothiazide) tablets, INFERGEN® – InterMune (Interferon alfacon-1), INVANZ® – Merck (ertapenem for injection), INVIRASE® – Roche Laboratories (saquinavir mesylate) Capsules, JANTOVEN? Some drugs can make food taste different, or they can cause a metallic, salty, or bitter taste in your mouth. Noticing things smell different or certain smells are stronger; Having a bitter or metallic taste in the mouth. Or use sports drinks to make frozen popsicles. © 2005 - 2021 WebMD LLC. Anything that causes a loss of sense of smell also damages taste as taste and smell are closely linked. Rees, T.D. Sugar is an added ingredient in many types of drug products, from vitamins and cough drops to antacids and syrup-based medications. – Odyssey (Albuterol Sulfate) Extended-Release Tablets, XANAX® – Pharmacia & Upjohn alprazolam tablets, ZEMPLAR® – Abbott (paricalcitol injection) Fliptop Vial, ZITHROMAX® – Pfizer (azithromycin Capsules) (azithromycin tablets) and (azithromycin for oral suspension), ZITHROMAX® – Pfizer (azithromycin for injection), ZITHROMAX® – Pfizer (azithromycin tablets) and (azithromycin for oral suspension), ZOSYN® – Wyeth-Ayerst (Piperacillin and Tazobactam for Injection), ZYPREXA – Lilly, IntraMuscular, Tablets, and ZYdis Orally Disintegrating Tablets, ZYRTEC® – Pfizer (cetirizine hydrochloride) Tablets, Chewable Tablets and Syrup, ZYRTEC-D 12 HOUR® – Pfizer (cetirizine hydrochloride) Extended Release Tablets, ZYVOX? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Duthie, E.H. Many other medicines have been linked to taste changes. GingerMuch like garlic, even ginger has beneficial properties in helping out with the condition … They might be described as: Not being able to smell things other people do, or noticing a reduced sense of smell. Prescription medication might be necessary for a disorder like Bell's palsy. Warnings and Medication Interactions. Some people call it medicine mouth, the drug companies refer to it as Taste perversion. Gum tissue becomes so swollen that it begins to grow over the teeth. Some drugs can reduce the amount of saliva in your mouth, causing an uncomfortably dry mouth (xerostomia). ", American Academy of Periodontology: "How to Keep a Healthy Smile for Life. Managing taste and smell changes. Mucositis causes painful swelling of the mouth and tongue and can lead to bleeding, pain, and mouth ulcers. Objective: Preclinical studies indicate that dopaminergic transmission in the basal ganglia may be involved in processing of both pleasant and unpleasant stimuli. Treating the underlying condition that causes your impaired sense of taste can help restore your taste. A sense of taste that is compromised could also affect a person’s appetite and enjoyment of their food. Many antibiotics cause a metallic taste in the mouth. The following medicines can cause brown, yellow-brown, or gray tooth discoloration: Too much fluoride (found in some chewable vitamins, toothpastes, and mouthwash) can lead to white streaks on the tooth enamel, or a whitish-brown discoloration. click here. Good oral hygiene and more frequent visits to the dentist (perhaps every three months) can help lower your chances of developing this condition. You are born with 9,000 taste buds, which work in tandem with your sense of smell as your sense of taste relies primarily on odors. Diabetes can increase your risk of altered taste, and diabetic neuropathy may play a role by damaging the nerves that perceive and interpret taste. Mouth ulcers are often compared to "craters" because they have a hole in the middle. A change in the body's ability to sense tastes is called dysgeusia. Updated 28 May 2011 ... Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Your sense of smell and taste change as you age. Penicillin, amoxicillin, Augmentin, and cephalosporins (Ancef, Keflex) are commonly prescribed for acute sore throat, and ear and sinus infections, and they may lead to a metallic taste in your mouth. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 … (Bummer.) Mouth sores may also be called canker sores. Medications can affect the taste buds and ion channels in taste-bud cell membranes involved in stimulus transduction. (lansoprazole) delayed-release Capsules and tablets, PRIMAXIN® I.M. All rights reserved. Candida is a normal organism in your mouth, but sometimes it can overgrow and cause symptoms.Oral thrush causes creamy white lesions, usually on your tongue or inner cheeks. August 2006. Mucositis is a common side effect of chemotherapy treatment. Continue Learning about Taste & The Nervous System Source material: Food and Drug Administration, Medline, Physician's Desk Reference, and the largest community of people in the world, those who are concerned about side effects and healthcare. Some medications can also affect our sense of smell or the amount of saliva that we produce — both of which are factors that can affect the taste of food just as much as our taste buds … "Â, Academy Of General Dentistry: "Treatments For Depression Have Dental Side Effects.". Medicines used to treat cancer, high blood pressure, severe pain, depression, allergies, and even the common cold, can have a negative impact on your dental health. Generally speaking, medicines are designed to make you feel better. More than 400 medications are known to cause dry mouth. WebMD does not provide medical advice, diagnosis or treatment. But all drugs, whether taken by mouth or injected, come with a risk of side effects, and hundreds of drugs are known to cause mouth (oral) problems. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Damage taste buds might mean someone is unable to taste spoiled foods. A dog’s sense of taste is much less discriminating than that of humans. There are many drugs that cause a change in your sense of taste. Philadelphia, Elsevier, 2007. Some medicines that list dry mouth as a side effect include: Dry mouth can be a bothersome problem. When a person takes tetracycline, some of the medicine settles into the calcium that the body uses to build teeth. Philadelphia, Saunders, 2008. – GlaxoSmithKline (paroxetine hydrochloride) Controlled-Release Tablets and Oral Suspension, PEG-INTRON® – Schering (Peginterferon alfa-2b) Powder for Injection, PEPCID® – Merck (Famotidine) Injection, Oral Suspension and Tablets, PLAVIX® – Bristol-Myers Squibb (clopidogrel bisulfate tablets), PLAVIX® – Sanofi-Synthelabo (clopidogrel bisulfate tablets), PRAVACHOL® – Bristol-Myers Squibb (pravastatin sodium) Tablets, PREVACID – TAP, Delayed-Release Capsules, Oral Suspension, I.V. However, certain citrus fruits, particularly grapefruit, can affect the way some medications work so check with your doctor or pharmacist first. Other medicines are believed to affect materials in or on existing teeth, causing staining. and Orally Disintegrating Tablets, PREVACID® NapraPAC? After about 8 to 10 hours, my sense of taste returns. The drugs listed in bold print have an incident rate of bad taste in 3% or more of patients. In the 1950s, doctors discovered that the use of tetracycline antibiotics during pregnancy led to brownish-color teeth in children. These drugs were representatives of the following classifications: psychotropic, cardiovascular, analgesic, anti-inflammatory, antihistamine, sedatives, antiemetic, antimicrobial, and antiviral. Some pain medications also can affect your sense of taste and smell. Having existing dental plaque also raises your risk. – 3M (flecainide acetate) Tablets, TIMENTIN® – GlaxoSmithKline (sterile ticarcillin disodium and clavulanate potassium) for Intravenous Administration ADD-VANTAGE® VIAL, TINDAMAX? The condition can make it difficult to eat. Certain drugs used to treat high blood pressure, such as amlodipine, diltiazem, and some ACE inhibitors, can interfere with smell. Philadelphia, Elsevier, 2007. Do not use this information as a substitute for your doctor's advice. Drink a mixture of one tablespoon of apple cider vinegar and 1/4 teaspoon of baking soda in … Some medications can cause a buildup of gum tissue, a condition called "gingival overgrowth." They include: Corticosteroids (used to treat inflammation). Most of materials presented are a layman's report and is not intended to replace discussions with a health care provider. Taste Changes Should Be Temporary . Photo: AdobeStock/Voyagerix The link to diabetes. Certain inhaler medications used for asthma may lead to a yeast infection in the mouth called oral candidiasis. Then it's time to take another capsule. Taste changes are especially common among elderly patients who take multiple medications. The next time you pop a pill, ask yourself this question: What will this medicine do to my mouth and teeth? This increases your risk for infection, tooth decay, and gum disease. Some medications can cause a bitter or metallic taste or affect the ability to taste. Try sharp, fresh-tasting foods like lemon, and drinks such as bitter lemon. – Pharmacia & Upjohn (linezolid) injection, tablets, and oral suspension. There were some nasal zinc products that were taken off the market because they were causing damage to the sense of taste. Some people call it medicine mouth, the drug companies refer to it as Taste perversion. Such drugs include: Other medicines that have been linked to the development of mouth sores include: Sometimes, a medication can alter your sense of taste. Also, previous treatments with chemotherapy can damage taste and cause lost taste. – Merck (Imipenem and Cilastatin), PRINZIDE® Tablets – Merck (Lisinopril-Hydrochlorothiazide), PROSOM? Tetracycline, however, does not cause tooth discoloration if taken after all teeth are formed. High blood sugar may also contribute to transient loss of taste.Altered taste in people with diabetes may also be caused by a change or loss of sense of smell, which affects someone’s … Periodontology 2000, October1998. Viral or bacterial infections. ‍Experiencing fatigue and lack of energy, even after a full night's sleep, … If you’re being treated for cancer, your sense of taste might be thrown off … Chemotherapy drugs that cause mucositis can cause mouth sores to develop. Ciancio, S. Journal of the American Dental Association, vol 135. Padala, K.P. Apple cider vinegar works to stimulate taste buds with its acidic and sour taste. American Pregnancy Association: "Acne treatment during pregnancy. Practice of Geriatrics, 4th ed. Saliva substitutes, such as those you spray into your mouth, may also be effective. or your stomach acid likes to travel. Acid reflux is caused by stomach acid going backwards … Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Inflammation of the Lining Inside of the Mouth (Mucositis), Slideshow: Dry Mouth: Causes, Symptoms, and Treatment, [ss_icon]15 Tooth Problems: Cavities, Stained Teeth, Hyperdontia and More, Tooth Discoloration: Foods That Stain Your Teeth, 5 Things You Didn’t Know About Your Teeth, Scopolamine, used to prevent motion sickness, amoxicillin-clavulanate (Augmentin), an antibiotic used to treat a number of bacterial infections, chlorhexidine, an antiseptic/disinfectant, doxycycline, an antibiotic related to tetracycline that is often used to treat acne, tetracycline, an antibiotic used to treat acne and some respiratory infections, ciprofloxacin (Cipro), an antibiotic known as a quinolone, minocycline, an antibiotic related to tetracycline. According to this case report, . – Upsher-Smith (Warfarin Sodium Tablets), KALETRA® – Abbott (lopinavir/ritonavir) Capsules and oral solution, KOGENATE® FS – Bayer health care, Antihemophilic Factor (Recombinant) Formulated with Sucrose, KYTRIL – Roche Laboratories (granisetron hydrochloride) Injection, LAMICTAL® – GlaxoSmithKline (lamotrigine) Tablets and Chewable Tablets, LAMISIL® – Novartis (terbinafine hydrochloride tablets) Tablets, LESCOL® – Novartis (fluvastatin sodium) Capsules, Tablets, LESCOL® – Reliant (fluvastatin sodium) Capsules, LESCOL® XL (fluvastatin sodium) Extended-Release Tablets, Levaquin – Ortho-McNeil, Injection, Tablets, in 5% Dextrose Injection, LOTRONEX® – GlaxoSmithKline (alosetron hydrochloride) Tablets, LUPRON DEPOT® – TAP (leuprolide acetate for depot suspension), LUPRON® – TAP (leuprolide acetate) Injection, MAXAIR? Long-term use of sweetened medications can lead to tooth decay. Quitting smoking has numerous health benefits, including restoring taste you lost to the habit. – Lilly (olanzapine and fluoxetine HCl Capsules), TAMBOCOR? Use wine, vinegar, or soy sauce to marinate your main meat dishes: fish, turkey, chicken, or beef. AUTOHALER? Use sugar-free candies and gum to get rid of bad tastes: mints, zinc lozenges, gum, etc. Between the ages of 40 and 50, the number of taste buds decreases, and the rest begin to shrink, losing mass vital to their operation. Rinse your mouth out after using such products, or ask your doctor or pharmacist if there is a sugar-free alternative. Swollen gum tissue creates a favorable environment for bacteria, which can damage surrounding tooth structures. Antibiotics can solve issues, such as sinusitis and salivary gland infections, that affect taste. Gingival overgrowth increases your risk of periodontal disease. When the teeth grow in, they are a yellowish-color, and they gradually turn brown when exposed to sunlight. and I.V. – Abbott (estazolam tablets) I.V. If you find yourself disliking your favorite foods, try foods that are different from what you normally eat. Eat cold or frozen foods to numb your taste buds: ice chips, fruit slushes, sorbet, sherbet, frozen grapes, or frozen pieces of watermelon, cantaloupe, or orange slices. Walsh, D. Palliative Medicine, 1st ed. Taste changes are especially common among elderly patients who take multiple medications. Some of the most common mouth-related (oral) side effects of medications are listed below. Other cardiovascular drugs that have been reported to alter taste include statins, clopidogrel (Plavix), and various beta blockers, calcium-channel … This tissue is called the mucous membrane. 375 – TAP (lansoprazole) delayed-release Capsules, Solu Tabs and tablets kit, PREVACID® NapraPAC? Below is a list of the drugs that can alter or change your sense of taste. Medications that can cause gum swelling and overgrowth include: Men are more likely to develop this side effect. The following drugs may cause greenish or a blue-green grayish color: Iron salts taken by mouth can lead to black teeth. To read feedback about bad breath, bitter taste, medicine mouth, or any kind of strange taste, etc. Extreme exhaustion. Try new foods. Some drugs can make food taste different, or they can cause a metallic, salty, or bitter taste in your mouth. Increase the amount of strong herbs and spices used in your food: garlic, rosemary, mustard, thyme, basil, oregano, chili powder, cumin, mint, or even onion. That's why your dentist, not just your doctor, should always know about all the medications you are taking, including over-the-counter products, vitamins, and supplements. Colds and the flu can be treated with antihistamines and decongestants. – Presutti (tinidazole) Tablets, TRILEPTAL® – Novartis (oxcarbazepine) Tablets, Oral Suspension, TORADOL® – Roche Laboratories (ketorolac tromethamine) IV/IM, Oral Suspension and tablets), UNIVASC® – Schwarz (moexipril hydrochloride) tablets, VANTIN® – Pharmacia & Upjohn (cefpodoxime proxetil) Tablets and Oral Suspension, VFEND® I.V. Food not having much taste. It only causes a change in tooth color if you take the medicine before the primary or secondary teeth come in. – Pfizer (voriconazole) for Injection, Tablets and Oral Suspension, VOSPIRE ER? At the first sign of a rash, stop taking the drug and see your doctor to determine whether it is the beginning of one of the severe skin reactions. Clinical Men's Health: Evidence in Practice, 1st ed. In fact, while humans have roughly 9,000 taste buds, dogs have only around 1,700. Without enough saliva, the tissues in the mouth can become irritated and inflamed. and Tablets, PROTOPIC® – Fujisawa (tacrolimus) Ointment 0.03% and 0.1%, REFACTO® – Wyeth-Ayerst Antihemophilic Factor, Recombinant, RELAFEN® – GlaxoSmithKline brand of nabumetone tablets, RELPAX® – Pfizer (eletriptan hydrobromide) Tablets, RESCRIPTOR® – Pfizer brand of delavirdine mesylate tablets, REYATAZ® – Bristol-Myers Squibb (atazanavir sulfate) Capsules, SALAGEN® – MGI (pilocarpine hydrochloride) Tablets, SANDOSTATIN LAR® DEPOT – Novartis (octreotide acetate for injectable suspension), SEROQUEL® – AstraZeneca (quetiapine fumarate), SPECTRACEF® – Purdue Pharmaceutical cefditoren pivoxil Tablets, SPORANOX® – Janssen (itraconazole) Oral Solution, STALEVO® – Novartis (carbidopa, levodopa and entacapone) Tablets, STRIANT® – Columbia (testosterone buccal system) mucoadhesive, SULAR® – First Horizon (Nisoldipine) Extended Release Tablets, SURMONTIL® – Odyssey (trimipramine maleate), SUSTIVA® – Bristol-Myers Squibb (efavirenz) Capsules and tablets, SYMBYAX? Chemotherapy drugs, including methotrexate and doxorubicin, are a common cause of taste changes.   Some people find that their taste buds are hypersensitive when they begin to taste things normally again, while other people find it to be a gradual process. Facial swelling, difficulty breathing or a feeling of your throat closing may be signs of a serious allergic reaction and require emergency care. Journal of the American Dental Association, June 2005. Initial transduction of taste stimuli occurs in taste buds, which are distributed in four discrete fields in the oral cavity.

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